Effect of Annexin V on Development of Apoptosis in Placental Syncytiotrophoblast Nuclei during Exacerbation of Cytomegalovirus Infection in the Third Trimester
- 作者: Lutsenko M.1, Andrievskaya I.1
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隶属关系:
- Far-Eastern Research Center of Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences
- 期: 卷 160, 编号 3 (2016)
- 页面: 327-329
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236698
- DOI: https://doi.org/10.1007/s10517-016-3162-3
- ID: 236698
如何引用文章
详细
During exacerbation of cytomegalovirus infection during pregnancy, cytomegalovirus proteins penetrate across the external membrane of placental villous syncytiotrophoblast and suppress activities of ATPase and Bcl-2 protein. Simultaneous increase in the content of annexin V and caspase 3 leads to structural disturbances in DNA in syncytiotrophoblast nuclei and stimulates their apoptosis. Structural abnormalities in the syncytiotrophoblast during exacerbation of cytomegalovirus infection are dangerous for fetal development.
作者简介
M. Lutsenko
Far-Eastern Research Center of Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences
编辑信件的主要联系方式.
Email: lucenkomt@mail.ru
俄罗斯联邦, Blagoveshchensk
I. Andrievskaya
Far-Eastern Research Center of Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences
Email: lucenkomt@mail.ru
俄罗斯联邦, Blagoveshchensk
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