Studying of the Mechanisms of Combined Effect of Dexamethasone, Doxorubicin, and Docetaxel on Breast Cancer Cells


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The sensitivity of MDA-MB231 breast cancer cells to the effects of pharmacological agents was evaluated by their motility and viability. Dexamethasone, doxorubicin, or docetaxel administered separately in their effective concentration suppressed cell motility (in 16 h) and caused cell death (in 48 h). The strength of the effects increased in the following order: dexa methasone

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E. Dukhanina

V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences

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Email: das03@rambler.ru
俄罗斯联邦, Moscow

T. Portseva

V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences; N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation

Email: das03@rambler.ru
俄罗斯联邦, Moscow; Moscow

A. Dukhanin

N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation

Email: das03@rambler.ru
俄罗斯联邦, Moscow

S. Georgieva

V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences

Email: das03@rambler.ru
俄罗斯联邦, Moscow

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