Efficiency of Umbilical Cord Blood Cells in Patients with Treatment-Resistant Depressions
- Авторы: Smulevich A.1, Dubnitskaya E.1, Voronova E.1, Morozova Y.2, Radaev S.3
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Учреждения:
- Research Center of Mental Health, Russian Academy of Medical Sciences
- Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation
- CryoCenter Umbilical Cord Blood Bank
- Выпуск: Том 160, № 4 (2016)
- Страницы: 583-588
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236812
- DOI: https://doi.org/10.1007/s10517-016-3222-8
- ID: 236812
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Аннотация
We studied the efficacy of umbilical cord blood cells in the therapy of treatment-resistant depressive states in women. Concentrated umbilical cord blood cells were administered in a dose of 250 millions cells (4 injections at 1-week intervals). The control group received placebo. In both groups, reduction of depressive disorders and the decrease in hypothymia severity were observed. Infusions of cell concentrate contributed to delayed correction of treatment resistance and reduced the severity of depression to moderate. In the main group, significant, persistent, and long-term positive dynamics was observed in the cognitive sphere. The therapeutic potential of umbilical cord blood cell concentrate can be used to overcome treatment resistance formed in depressive patients.
Об авторах
A. Smulevich
Research Center of Mental Health, Russian Academy of Medical Sciences
Email: yanamorozova0@gmail.com
Россия, Moscow
E. Dubnitskaya
Research Center of Mental Health, Russian Academy of Medical Sciences
Email: yanamorozova0@gmail.com
Россия, Moscow
E. Voronova
Research Center of Mental Health, Russian Academy of Medical Sciences
Email: yanamorozova0@gmail.com
Россия, Moscow
Ya. Morozova
Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: yanamorozova0@gmail.com
Россия, Moscow
S. Radaev
CryoCenter Umbilical Cord Blood Bank
Email: yanamorozova0@gmail.com
Россия, Moscow