Отправить статью по E-mail Quantitative PCR studies of Aggregatibacter actinomycetemcomitans and Treponema denticola/Tanerella forsythensis Complex as Etiological Factors of Chronic Periodontitis
- Авторы: Yanushevich O.1, Ayvazova R.1, Shibaeva A.2,3, Rebrikov D.4, Trubnikova E.5, Kudykina Y.3, Zylnikova M.3,6, Zaripova R.6, Shevelev A.3
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Учреждения:
- A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Health of the Russian Federation
- N. M. Emanuel Institute of Biochemical Physics, the Russian Academy of Sciences
- M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, the Russian Academy of Medical Sciences
- N. I. Vavilov Institute of Common Genetics, the Russian Academy of Sciences
- Kursk State University
- Naberezhnye Chelny Institute of Socio-Pedagogical Technologies and Resources
- Выпуск: Том 160, № 4 (2016)
- Страницы: 495-497
- Раздел: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/236754
- DOI: https://doi.org/10.1007/s10517-016-3205-9
- ID: 236754
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Аннотация
Real-time quantitative PCR (Dentofl or kit) was used to detect DNA of periodontal pathogens in specimens from 92 patients with chronic periodontitis and from a control sample of 12 normal subjects. A bimodal distribution of patients by periodontium colonization with A. actinomycetemcomitans, P. gingivalis, P. intermedia, T. forsythensis, and T. denticola was demonstrated. A new approach to interpretation of the results of quantitative evaluation of periodontal pathogens, including the notion of pathological colonization level, led to classification of all cases with chronic generalized periodontitis into 3 groups: associated with A. actinomycetemcomitans, with T. forsythensis/T. denticola complex, and cases of uncertain genesis.
Об авторах
O. Yanushevich
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Health of the Russian Federation
Email: a_reg@mail.ru
Россия, Moscow
R. Ayvazova
A. I. Evdokimov Moscow State University of Medicine and Dentistry, the Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: a_reg@mail.ru
Россия, Moscow
A. Shibaeva
N. M. Emanuel Institute of Biochemical Physics, the Russian Academy of Sciences; M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, the Russian Academy of Medical Sciences
Email: a_reg@mail.ru
Россия, Moscow; Moscow
D. Rebrikov
N. I. Vavilov Institute of Common Genetics, the Russian Academy of Sciences
Email: a_reg@mail.ru
Россия, Moscow
E. Trubnikova
Kursk State University
Email: a_reg@mail.ru
Россия, Kursk
Yu. Kudykina
M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, the Russian Academy of Medical Sciences
Email: a_reg@mail.ru
Россия, Moscow
M. Zylnikova
M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, the Russian Academy of Medical Sciences; Naberezhnye Chelny Institute of Socio-Pedagogical Technologies and Resources
Email: a_reg@mail.ru
Россия, Moscow; Naberezhnye Chelny
R. Zaripova
Naberezhnye Chelny Institute of Socio-Pedagogical Technologies and Resources
Email: a_reg@mail.ru
Россия, Naberezhnye Chelny
A. Shevelev
M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitides, the Russian Academy of Medical Sciences
Email: a_reg@mail.ru
Россия, Moscow
