Enviar artigo por via de e-mail Antioxidant Properties of Glial Cell-Derived Neurotrophic Factor (GDNF)
- Autores: Mishchenko T.1, Mitroshina E.1, Shishkina T.1, Vedunova M.1
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Afiliações:
- N. I. Lobachevsky Nizhny Novgorod National Research State University
- Edição: Volume 166, Nº 2 (2018)
- Páginas: 293-296
- Seção: Methods
- URL: https://journals.rcsi.science/0007-4888/article/view/240979
- DOI: https://doi.org/10.1007/s10517-018-4335-z
- ID: 240979
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Resumo
We propose an in vitro model of chronic oxidative stress based on the use of glucose oxidase. Oxidative stress modeling leads to a significant increase in the number of dead cells in culture. It was shown that the glial cell-derived neurotrophic factor exhibits a pronounced anti-oxidant effect. Preventive application of 1 ng/ml glial cell-derived neurotrophic factor significantly reduced the percentage of dead cells in culture.
Sobre autores
T. Mishchenko
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: mvedunova@yandex.ru
Rússia, Nizhny Novgorod
E. Mitroshina
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: mvedunova@yandex.ru
Rússia, Nizhny Novgorod
T. Shishkina
N. I. Lobachevsky Nizhny Novgorod National Research State University
Email: mvedunova@yandex.ru
Rússia, Nizhny Novgorod
M. Vedunova
N. I. Lobachevsky Nizhny Novgorod National Research State University
Autor responsável pela correspondência
Email: mvedunova@yandex.ru
Rússia, Nizhny Novgorod
