Level of Interleukins IL-6 and IL-15 in Blood Plasma of Mice after Forced Swimming Test
- Autores: Kapilevich L.1,2, Kironenko T.1, Zakharova A.1, Kabachkova A.1, Orlov S.1,3,4
-
Afiliações:
- Tomsk National Research State University
- National Research Tomsk Polytechnic University
- M. V. Lomonosov Moscow State University
- University of Montreal Health Center
- Edição: Volume 163, Nº 1 (2017)
- Páginas: 10-13
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238610
- DOI: https://doi.org/10.1007/s10517-017-3725-y
- ID: 238610
Citar
Resumo
We measured the concentrations of IL-6 and IL-15 in blood plasma of mice at different terms after forced swimming, taking into account exercise intensity and preliminary training. It was shown that training was an important factor affecting blood plasma level of IL both at rest and after single forced swimming: in trained animals, the concentration of both myokines increased immediately after swimming, while in untrained animals, this increase was observed only after 5 h. Changes in cytokine production against the background of training can be associated with various factors, including neuroendocrine mechanisms, stress, modification of intracellular signaling, as well as reorganization of transcriptional mechanisms in muscle fibers. The most important factor is shift in the ratio of monovalent cations (sodium and potassium) in the cytoplasm.
Sobre autores
L. Kapilevich
Tomsk National Research State University; National Research Tomsk Polytechnic University
Autor responsável pela correspondência
Email: kapil@yandex.ru
Rússia, Tomsk; Tomsk
T. Kironenko
Tomsk National Research State University
Email: kapil@yandex.ru
Rússia, Tomsk
A. Zakharova
Tomsk National Research State University
Email: kapil@yandex.ru
Rússia, Tomsk
A. Kabachkova
Tomsk National Research State University
Email: kapil@yandex.ru
Rússia, Tomsk
S. Orlov
Tomsk National Research State University; M. V. Lomonosov Moscow State University; University of Montreal Health Center
Email: kapil@yandex.ru
Rússia, Tomsk; Moscow; Montreal