Plant Polysaccharides Attenuate Fluorouracil Toxicity for the Small Intestinal Epithelium
- Autores: Safonova E.1, Lopatina K.1, Vychuzhanina A.1, Ermolaeva L.1, Razina T.1, Zueva E.1
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Afiliações:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- Edição: Volume 161, Nº 2 (2016)
- Páginas: 308-311
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237366
- DOI: https://doi.org/10.1007/s10517-016-3402-6
- ID: 237366
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Resumo
Polysaccharides from Tussilago farfara L., Acorus calamus L., and Echinacea purpurea (L.) Moench attenuated the toxic effect of fl uorouracil on the small intestinal epithelium of mice with Lewis lung carcinoma. Addition of polysaccharides to chemotherapy protocols stimulated reparative regeneration processes in the small intestine damaged by the cytostatic treatment. No stimulating effects of the polysaccharides on tumor growth and metastasizing were revealed.
Sobre autores
E. Safonova
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Autor responsável pela correspondência
Email: safonova_7@mail.ru
Rússia, Tomsk
K. Lopatina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: safonova_7@mail.ru
Rússia, Tomsk
A. Vychuzhanina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: safonova_7@mail.ru
Rússia, Tomsk
L. Ermolaeva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: safonova_7@mail.ru
Rússia, Tomsk
T. Razina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: safonova_7@mail.ru
Rússia, Tomsk
E. Zueva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: safonova_7@mail.ru
Rússia, Tomsk