Association of Regulatory and Adaptive Status in Humans with Serotonergic Transmitter System Gene Polymorphism


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Аннотация

The regulatory and adaptive status was determined in 202 healthy subjects by the parameters of the cardiorespiratory synchronism probe. We performed molecular-genetic analysis of polymorphic variants of the main gene of serotonin biosynthesis, tryptophan hydroxylase TPH1 (A218C polymorphism) and TPH2 (G703T polymorphism), and serotonin receptors (HTR2C and HTR2A genes). The association of the regulatory and adaptive status of a subject with the polymorphism of serotonergic mediator system genes was revealed.

Авторлар туралы

V. Pokrovskii

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Хат алмасуға жауапты Автор.
Email: pokrovsky@ksma.ru
Ресей, Krasnodar

Yu. Kashina

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Email: pokrovsky@ksma.ru
Ресей, Krasnodar

O. Kiek

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Email: pokrovsky@ksma.ru
Ресей, Krasnodar

O. Gumerova

Center for Molecular Genetic Studies, Department of Genetics, Bashkir State Pedagogical University

Email: pokrovsky@ksma.ru
Ресей, Ufa, Republic of Bashkortostan

V. Gorbunova

Center for Molecular Genetic Studies, Department of Genetics, Bashkir State Pedagogical University

Email: pokrovsky@ksma.ru
Ресей, Ufa, Republic of Bashkortostan

V. Abushkevich

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Email: pokrovsky@ksma.ru
Ресей, Krasnodar

A. Penzhoyan

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Email: pokrovsky@ksma.ru
Ресей, Krasnodar

N. Zabolotskikh

Department of Normal Physiology, Kuban State Medical University, Ministry of Health of the Russian Federation

Email: pokrovsky@ksma.ru
Ресей, Krasnodar

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