Мақаланы E-mail арқылы жіберу Effect of 30-Day Hindlimb Unloading and Hypergravity on Bone Marrow Stromal Progenitors in C57Bl/6N Mice
- Авторлар: Markina E.1, Andrianova I.1, Shtemberg A.1, Buravkova L.1
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Мекемелер:
- State Research Center Institute of Biomedical Problems, Russian Academy of Sciences
- Шығарылым: Том 166, № 1 (2018)
- Беттер: 130-134
- Бөлім: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/240868
- DOI: https://doi.org/10.1007/s10517-018-4301-9
- ID: 240868
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
We studied the effect of 30-day hindlimb unloading and subsequent simulated hypergravity on the cellularity and proliferative, clonogenic, and differentiation potential of bone marrow stromal progenitors in mice. Clonogenic and differentiation activity of stromal cells decreased after unloading; proliferative and differentiation activity of bone marrow stromal progenitors increased after hypergravity simulation. Our findings demonstrated negative effect of unloading on functional activity of mouse bone marrow stromal progenitors. Short-term hypergravity after unloading produced a stimulating effect on the bone marrow stromal progenitors.
Авторлар туралы
E. Markina
State Research Center Institute of Biomedical Problems, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: goncharova-tim@list.ru
Ресей, Moscow
I. Andrianova
State Research Center Institute of Biomedical Problems, Russian Academy of Sciences
Email: goncharova-tim@list.ru
Ресей, Moscow
A. Shtemberg
State Research Center Institute of Biomedical Problems, Russian Academy of Sciences
Email: goncharova-tim@list.ru
Ресей, Moscow
L. Buravkova
State Research Center Institute of Biomedical Problems, Russian Academy of Sciences
Email: goncharova-tim@list.ru
Ресей, Moscow
