Мақаланы E-mail арқылы жіберу Effect of Chronic Administration of Obestatin and Its Fragment FNAP-NH2 on Behavioral Activity and Nociceptive Threshold in Rats with Normal and Excess Body Weight
- Авторлар: Khirazova E.E.1, Motorykina E.S.1, Maslova M.V.1, Maklakova A.S.1, Graf A.V.1,2, Sokolova N.A.1, Kamenskii A.A.1
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Мекемелер:
- Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
- Department of Nano-, Bio-, Information Technology, and Cognitive Science, Moscow Institute of Physics and Technology (MIPT)
- Шығарылым: Том 163, № 3 (2017)
- Беттер: 293-295
- Бөлім: Physiology
- URL: https://journals.rcsi.science/0007-4888/article/view/238837
- DOI: https://doi.org/10.1007/s10517-017-3787-x
- ID: 238837
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The effects of chronic intranasal administration of 300 nmol/kg obestatin and its fragment FNAP-NH2 on behavioral activity and nociceptive threshold were examined in male Wistar rats with normal body weight or alimentary obesity. In normal rats, obestatin produced no effect on behavior and nociception, whereas FNAP-NH2 fragment enhanced risk-taking behavior. Rats with excess body weight demonstrated less pronounced risk-taking behavior and elevated nociceptive threshold in comparison with normal animals, but these differences were abolished by chronic administration of FNAP-NH2.
Авторлар туралы
E. Khirazova
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Хат алмасуға жауапты Автор.
Email: ekhirazova@gmail.com
Ресей, Moscow
E. Motorykina
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Email: ekhirazova@gmail.com
Ресей, Moscow
M. Maslova
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Email: ekhirazova@gmail.com
Ресей, Moscow
A. Maklakova
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Email: ekhirazova@gmail.com
Ресей, Moscow
A. Graf
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University; Department of Nano-, Bio-, Information Technology, and Cognitive Science, Moscow Institute of Physics and Technology (MIPT)
Email: ekhirazova@gmail.com
Ресей, Moscow; Moscow
N. Sokolova
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Email: ekhirazova@gmail.com
Ресей, Moscow
A. Kamenskii
Department of Human and Animal Physiology, Faculty of Biology, M. V. Lomonosov Moscow State University
Email: ekhirazova@gmail.com
Ресей, Moscow
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