Expression of Surface Molecules in Human Mesenchymal Stromal Cells Co-Cultured with Nucleated Umbilical Cord Blood Cells
- Авторлар: Romanov Y.1,2, Balashova E.2, Volgina N.3, Kabaeva N.1, Dugina T.2, Sukhikh G.3
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Мекемелер:
- Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation
- CryoCenter Cord Blood Bank
- V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- Шығарылым: Том 162, № 4 (2017)
- Беттер: 578-582
- Бөлім: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/238387
- DOI: https://doi.org/10.1007/s10517-017-3662-9
- ID: 238387
Дәйексөз келтіру
Аннотация
We studied the expression of different classes of surface molecules (CD13, CD29, CD40, CD44, CD54, CD71, CD73, CD80, CD86, CD90, CD105, CD106, CD146, HLA-I, and HLA-DR) in mesenchymal stromal cells from human umbilical cord and bone marrow during co-culturing with nucleated umbilical cord blood cells. Expression of the majority of surface markers in both types of mesenchymal stromal cells was stable and did not depend on the presence of the blood cells. Significant differences were found only for cell adhesion molecules CD54 (ICAM-1) and CD106 (VCAM-1) responsible for direct cell—cell contacts with leukocytes and only for bone marrow derived cells.
Авторлар туралы
Yu. Romanov
Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation; CryoCenter Cord Blood Bank
Хат алмасуға жауапты Автор.
Email: romanov@cardio.ru
Ресей, Moscow; Moscow
E. Balashova
CryoCenter Cord Blood Bank
Email: romanov@cardio.ru
Ресей, Moscow
N. Volgina
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cardio.ru
Ресей, Moscow
N. Kabaeva
Russian Cardiology Research-and-Production Complex, Ministry of Health of the Russian Federation
Email: romanov@cardio.ru
Ресей, Moscow
T. Dugina
CryoCenter Cord Blood Bank
Email: romanov@cardio.ru
Ресей, Moscow
G. Sukhikh
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: romanov@cardio.ru
Ресей, Moscow