Sources of Reactive Oxygen and Nitrogen Species in Tissue Microenvironment of Hernioplasty Materials
- Авторлар: Sarbaeva N.1, Ponomareva Y.1, Milyakova M.1, Gribkova O.1
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Мекемелер:
- Institute of Experimental Medicine and Biotechnologies, Samara State Medical University, the Ministry of Health of the Russian Federation
- Шығарылым: Том 161, № 5 (2016)
- Беттер: 711-714
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237698
- DOI: https://doi.org/10.1007/s10517-016-3491-2
- ID: 237698
Дәйексөз келтіру
Аннотация
Titanium and polypropylene mesh endoprostheses were implanted into the rat abdominal cavity and the populations of cells migrating to their surface were analyzed. On both materials, the cells were presented mainly by macrophages that proliferated, activated, and fused to form multinuclear cells. Contact with the foreign surface triggered superoxide anion generation and myeloperoxidase synthesis by macrophages (these processes were more intense on polypropylene implants than on titanium ones) and stimulated production of nitric oxide by macrophage. It was hypothesized that the effects of free nitrogen and oxygen radicals lead to oxidation and destruction of the polypropylene endoprosthesis surface.
Авторлар туралы
N. Sarbaeva
Institute of Experimental Medicine and Biotechnologies, Samara State Medical University, the Ministry of Health of the Russian Federation
Email: jvponomareva@mail.ru
Ресей, Samara
Yu. Ponomareva
Institute of Experimental Medicine and Biotechnologies, Samara State Medical University, the Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: jvponomareva@mail.ru
Ресей, Samara
M. Milyakova
Institute of Experimental Medicine and Biotechnologies, Samara State Medical University, the Ministry of Health of the Russian Federation
Email: jvponomareva@mail.ru
Ресей, Samara
O. Gribkova
Institute of Experimental Medicine and Biotechnologies, Samara State Medical University, the Ministry of Health of the Russian Federation
Email: jvponomareva@mail.ru
Ресей, Samara