Effect of Hepatitis C Virus Coinfection on the Content of CD4+ and CD8+ T Cell Subpopulations in HIV-Infected Patients Receiving Antiretroviral Therapy


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4+ T cells and an increase in the count of central CD8+ memory T cells in these patients. Hepatitis C virus had no effect on the number of CD4+ memory T cells (main target for HIV). This can explain the absence of strong negative effect of hepatitis C virus on the course of HIV infection.

Авторлар туралы

L. Korolevskaya

Perm State National Research University; Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: bioqueen@mail.ru
Ресей, Perm; Ekaterinburg

K. Shmagel

Perm State National Research University; Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences

Email: bioqueen@mail.ru
Ресей, Perm; Ekaterinburg

E. Saidakova

Perm State National Research University; Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences

Email: bioqueen@mail.ru
Ресей, Perm; Ekaterinburg

N. Shmagel

Perm State National Research University; Perm Regional Center for Prevention of AIDS and Infectious Diseases

Email: bioqueen@mail.ru
Ресей, Perm; Perm

S. Slobodchikova

Perm State National Research University; Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences

Email: bioqueen@mail.ru
Ресей, Perm; Ekaterinburg

V. Chereshnev

Perm State National Research University; Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences; Ural Federal University Named after the First President of Russia B. N. Yeltsin

Email: bioqueen@mail.ru
Ресей, Perm; Ekaterinburg; Ekaterinburg


© Springer Science+Business Media New York, 2016

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>