Effects of NO Donors and Inhibitors of NO Synthase and Guanylate Cyclase on the Acquisition of a Conditioned Defense Food Aversion Response in Edible Snails
- Авторлар: Muranova L.1, Bogodvid T.1, Andrianov V.1, Gainutdinov K.1
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Мекемелер:
- Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University
- Шығарылым: Том 160, № 4 (2016)
- Беттер: 414-416
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236720
- DOI: https://doi.org/10.1007/s10517-016-3184-x
- ID: 236720
Дәйексөз келтіру
Аннотация
Experiments on edible snails revealed that NO synthase blockade with a nonspecific neuronal NO synthase inhibitor L-NAME before defense food aversion conditioning is followed by a decrease in the rate of learning. Exogenous NO donors, sodium nitroprusside and dinitrosyl iron complex, were shown to improve learning. Chronic administration of a specific soluble guanylate cyclase inhibitor ODQ also increased the rate of learning. Our results indicate that NO has a modulatory effect on the formation of a conditioned response in this type of learning.
Авторлар туралы
L. Muranova
Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University
Email: kh_gainotdinov@mail.ru
Ресей, Kazan
T. Bogodvid
Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University
Email: kh_gainotdinov@mail.ru
Ресей, Kazan
V. Andrianov
Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University
Email: kh_gainotdinov@mail.ru
Ресей, Kazan
Kh. Gainutdinov
Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University
Хат алмасуға жауапты Автор.
Email: kh_gainotdinov@mail.ru
Ресей, Kazan