Surface Molecular Markers of Cancer Stem Cells: Computation Analysis of Full-Text Scientific Articles
- Authors: Suvorov R.E.1, Kim Y.S.2, Gisina A.M.2, Chiang J.H.3, Yarygin K.N.2, Lupatov A.Y.2
-
Affiliations:
- Federal Research Center Computer Science and Control, Russian Academy of Sciences
- V. N. Orekhovich Research Institute of Biomedical Chemistry
- National Cheng Kung University
- Issue: Vol 166, No 1 (2018)
- Pages: 135-140
- Section: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/240871
- DOI: https://doi.org/10.1007/s10517-018-4302-8
- ID: 240871
Cite item
Abstract
The data on cancer stem cell surface molecular markers of 27 most common cancer diseases were analyzed using natural language processing and data mining techniques. As a source, 8933 full-text open-access English-language scientific articles available on the Internet were used. Text mining was based on searching for three entities within one sentence, namely a tumor name, a phrase “cancer stem cells” or its synonym, and a name of differentiation cluster molecule. As a result, a list of surface molecular markers was formed that included markers most frequently mentioned in the context of certain tumor diseases and used in studies of human and animal tumor cells. Based on similarity of the associated markers, the tumors were divided into five groups.
About the authors
R. E. Suvorov
Federal Research Center Computer Science and Control, Russian Academy of Sciences
Email: alupatov@mail.ru
Russian Federation, Moscow
Ya. S. Kim
V. N. Orekhovich Research Institute of Biomedical Chemistry
Email: alupatov@mail.ru
Russian Federation, Moscow
A. M. Gisina
V. N. Orekhovich Research Institute of Biomedical Chemistry
Email: alupatov@mail.ru
Russian Federation, Moscow
J. H. Chiang
National Cheng Kung University
Email: alupatov@mail.ru
Taiwan, Province of China, Tainan City
K. N. Yarygin
V. N. Orekhovich Research Institute of Biomedical Chemistry
Email: alupatov@mail.ru
Russian Federation, Moscow
A. Yu. Lupatov
V. N. Orekhovich Research Institute of Biomedical Chemistry
Author for correspondence.
Email: alupatov@mail.ru
Russian Federation, Moscow