Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax
- Authors: Gavrilova S.A.1, Markov M.A.1, Berdalin A.B.1, Kurenkova A.D.1, Koshelev V.B.1
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Affiliations:
- Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
- Issue: Vol 163, No 5 (2017)
- Pages: 617-619
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239126
- DOI: https://doi.org/10.1007/s10517-017-3862-3
- ID: 239126
Cite item
Abstract
The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction. In 28 days after ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of ventricular septum, although it produced no effect on the density of β1 and β2 adrenoceptors.
About the authors
S. A. Gavrilova
Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Email: alex_berdalin@mail.ru
Russian Federation, Moscow
M. A. Markov
Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Email: alex_berdalin@mail.ru
Russian Federation, Moscow
A. B. Berdalin
Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Author for correspondence.
Email: alex_berdalin@mail.ru
Russian Federation, Moscow
A. D. Kurenkova
Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Email: alex_berdalin@mail.ru
Russian Federation, Moscow
V. B. Koshelev
Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Email: alex_berdalin@mail.ru
Russian Federation, Moscow