Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax


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Abstract

The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction. In 28 days after ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of ventricular septum, although it produced no effect on the density of β1 and β2 adrenoceptors.

About the authors

S. A. Gavrilova

Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University

Email: alex_berdalin@mail.ru
Russian Federation, Moscow

M. A. Markov

Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University

Email: alex_berdalin@mail.ru
Russian Federation, Moscow

A. B. Berdalin

Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University

Author for correspondence.
Email: alex_berdalin@mail.ru
Russian Federation, Moscow

A. D. Kurenkova

Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University

Email: alex_berdalin@mail.ru
Russian Federation, Moscow

V. B. Koshelev

Department of Physiology and General Pathology, Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University

Email: alex_berdalin@mail.ru
Russian Federation, Moscow


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