Parameters of Blood Flow in Great Arteries in Hypertensive ISIAH Rats with Stress-Dependent Arterial Hypertension
- Authors: Seryapina A.A.1, Shevelev O.B.1, Moshkin M.P.1,2, Markel’ A.L.1,2
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Affiliations:
- Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Novosibirsk State University
- Issue: Vol 161, No 4 (2016)
- Pages: 468-471
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237520
- DOI: https://doi.org/10.1007/s10517-016-3440-0
- ID: 237520
Cite item
Abstract
Magnetic resonance angiography was used to examine blood flow in great arteries of hypertensive ISIAH and normotensive Wistar rats. In hypertensive ISIAH rats, increased vascular resistance in the basin of the abdominal aorta and renal arteries as well as reduced fraction of total renal blood flow were found. In contrast, blood flow through both carotid arteries in ISIAH rats was enhanced, which in suggests more intensive blood supply to brain regulatory centers providing enhanced stress reactivity of these rats characterized by stress-dependent arterial hypertension.
About the authors
A. A. Seryapina
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Author for correspondence.
Email: seryapina@bionet.nsc.ru
Russian Federation, Novosibirsk
O. B. Shevelev
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: seryapina@bionet.nsc.ru
Russian Federation, Novosibirsk
M. P. Moshkin
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; Novosibirsk State University
Email: seryapina@bionet.nsc.ru
Russian Federation, Novosibirsk; Novosibirsk
A. L. Markel’
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; Novosibirsk State University
Email: seryapina@bionet.nsc.ru
Russian Federation, Novosibirsk; Novosibirsk