MicroRNA hsa-miR-4674 in Hemolysis-Free Blood Plasma Is Associated with Distant Metastases of Prostatic Cancer

E. N. Knyazev; T. R. Samatov; K. A. Fomicheva; K. M. Nyushko; B. Ya. Alekseev; M. Yu. Shkurnikov

doi:10.1007/s10517-016-3358-6

MicroRNA hsa-miR-4674 in Hemolysis-Free Blood Plasma Is Associated with Distant Metastases of Prostatic Cancer

Authors: Knyazev E.N.¹, Samatov T.R.¹, Fomicheva K.A.², Nyushko K.M.², Alekseev B.Y.², Shkurnikov M.Y.¹^,2
Affiliations:
1. BioClinicum Research and Development Center
2. National Medical Research Radiology Center
Issue: Vol 161, No 1 (2016)
Pages: 112-115
Section: Article
URL: https://journals.rcsi.science/0007-4888/article/view/237169
DOI: https://doi.org/10.1007/s10517-016-3358-6
ID: 237169

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Abstract

We analyzed microRNA profile in hemolysis-free blood plasma of patients with prostatic cancer. The metastatic form of prostatic cancer was found to be associated with increased levels of hsa-miR-22-3p, hsa-miR-663a, and hsa-miR-4674 in comparison with non-metastatic form. Common candidate target genes of these microRNA include JUNB, KMT2A, and XPO6.