Changes of the Expression of Neuronal NO-Synthase in Rat Sympathetic Ganglia during Ontogeny
- Authors: Moiseev K.Y.1, Yukhmankova A.V.1, Masliukov P.M.1,2
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Affiliations:
- Yaroslalv State Medical University, Ministry of Health of the Russian Federation
- Petrozavodsk State University
- Issue: Vol 168, No 1 (2019)
- Pages: 76-78
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242233
- DOI: https://doi.org/10.1007/s10517-019-04651-5
- ID: 242233
Cite item
Abstract
Expression of neuronal NO synthase in the sympathetic cranial cervical ganglion and stellate ganglion in rats during postnatal ontogeny was studied by immunohistochemistry and Western blotting. In the sympathetic ganglia, neuronal NO synthase-immunoreactive neurons were absent in all rats. In the stellate and cranial cervical ganglia, the expression of neuronal NO synthase and the density of immunoreactive fibers increased in early postnatal ontogeny from the moment of birth to the age of 30 days and then decreased. Thus, we observed heterochroneous expression of neuronal NOS in the preganglionic somata in the spinal cord and in the preganglionic fibers in the sympathetic ganglia during ontogeny.
About the authors
K. Yu. Moiseev
Yaroslalv State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
Russian Federation, Yaroslavl
A. V. Yukhmankova
Yaroslalv State Medical University, Ministry of Health of the Russian Federation
Email: mpm@ysmu.ru
Russian Federation, Yaroslavl
P. M. Masliukov
Yaroslalv State Medical University, Ministry of Health of the Russian Federation; Petrozavodsk State University
Author for correspondence.
Email: mpm@ysmu.ru
Russian Federation, Yaroslavl; Petrozavodsk
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