Email this article Composition and Structure of Gut Microbiome in Adolescents with Obesity and Different Breastfeeding Duration
- Authors: Belkova N.L.1,2, Nemchenko U.M.1, Pogodina A.V.1, Feranchuk S.I.2,3, Romanitsa A.I.1, Novikova E.A.1, Rychkova L.V.1
-
Affiliations:
- Research Center for Family Health and Human Reproduction Problems
- Limnological Institute, Siberian Division of the Russian Academy of Sciences
- Irkutsk National Research Technical University
- Issue: Vol 167, No 6 (2019)
- Pages: 759-762
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242095
- DOI: https://doi.org/10.1007/s10517-019-04617-7
- ID: 242095
Cite item
Open Access
Access granted
Subscription Access
Abstract
Gut microbiome of adolescents with obesity and different duration of breastfeeding was analyzed by metagenomic analysis of V3-V4 variable domains of the 16S rRNA gene. In subgroup with breastfeeding duration <3 months, intrapopulation structure of gut microbiome by alpha diversity indices was similar in adolescents with obesity and normal body weight. The decrease in phylotype abundance in the structure of communities was associated only with obesity, while dysbiotic state persisted in both lean and overweight adolescents, which confirmed the effect of breastfeeding duration on stability of gut microbiome.
About the authors
N. L. Belkova
Research Center for Family Health and Human Reproduction Problems; Limnological Institute, Siberian Division of the Russian Academy of Sciences
Author for correspondence.
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk; Irkutsk
U. M. Nemchenko
Research Center for Family Health and Human Reproduction Problems
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk
A. V. Pogodina
Research Center for Family Health and Human Reproduction Problems
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk
S. I. Feranchuk
Limnological Institute, Siberian Division of the Russian Academy of Sciences; Irkutsk National Research Technical University
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk; Irkutsk
A. I. Romanitsa
Research Center for Family Health and Human Reproduction Problems
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk
E. A. Novikova
Research Center for Family Health and Human Reproduction Problems
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk
L. V. Rychkova
Research Center for Family Health and Human Reproduction Problems
Email: nlbelkova@gmail.com
Russian Federation, Irkutsk
