Correction of Damaging Effects of Cisplatin-Containing Polychemotherapy on the Intestinal Epithelium with  Tussilago farfara  L. Polysaccharides

E. A. Safonova; K. A. Lopatina; T. G. Razina; E. P. Zueva; L. A. Sadrikina; A. M. Gur’ev; M. V. Belousov

doi:10.1007/s10517-019-04582-1

Correction of Damaging Effects of Cisplatin-Containing Polychemotherapy on the Intestinal Epithelium with Tussilago farfara L. Polysaccharides

Authors: Safonova E.A.¹, Lopatina K.A.¹, Razina T.G.¹, Zueva E.P.¹, Sadrikina L.A.¹, Gur’ev A.M.², Belousov M.V.²
Affiliations:
1. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center
2. Siberian State Medical University, Ministry of Healthcare of the Russian Federation
Issue: Vol 167, No 5 (2019)
Pages: 616-620
Section: Article
URL: https://journals.rcsi.science/0007-4888/article/view/241963
DOI: https://doi.org/10.1007/s10517-019-04582-1
ID: 241963

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Abstract

A possibility for correction of damaging effects of polychemotherapy on the intestinal epithelium with Tussilago farfara L. polysaccharides was studied on C57Bl/6 mice with Lewis lung carcinoma. The polysaccharides had protective and/or stimulating effects on the intestinal epithelium during polychemotherapy and promoted reparative regeneration in the intestine.