Email this article Contractile Activity of Lymph Nodes in Young, Middle-Aged, and Old Rats
- Authors: Demchenko G.A.1, Abdreshov S.N.1, Nurmakhanova B.A.1
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Affiliations:
- Laboratory of Lymphatic System Physiology, Institute of Human and Animal Physiology, Ministry of Education and Science of the Republic of Kazakhstan
- Issue: Vol 167, No 2 (2019)
- Pages: 194-197
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241578
- DOI: https://doi.org/10.1007/s10517-019-04489-x
- ID: 241578
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Abstract
We studied age-associated changes in contractile activity of isolated cervical and mesenteric lymph nodes in rats. In young and middle-aged rats, no significant changes in contractile activity of lymph nodes were revealed. In old rats, the amplitude of spontaneous contractions of lymph nodes was lower and their rate was higher than in young and middle-aged animals; the sensitivity of lymph nodes to vasoactive agents was reduced and the threshold of the response was higher in old rats.
About the authors
G. A. Demchenko
Laboratory of Lymphatic System Physiology, Institute of Human and Animal Physiology, Ministry of Education and Science of the Republic of Kazakhstan
Email: bbm.ktbm@gmail.com
Kazakhstan, Almaty
S. N. Abdreshov
Laboratory of Lymphatic System Physiology, Institute of Human and Animal Physiology, Ministry of Education and Science of the Republic of Kazakhstan
Email: bbm.ktbm@gmail.com
Kazakhstan, Almaty
B. A. Nurmakhanova
Laboratory of Lymphatic System Physiology, Institute of Human and Animal Physiology, Ministry of Education and Science of the Republic of Kazakhstan
Email: bbm.ktbm@gmail.com
Kazakhstan, Almaty
