Email this article Structure of Rat Testicles after Intravenous Injection of Nanosized Magnetite Particles
- Authors: Mil’to I.V.1, Sukhodolo I.V.1, Ivanova V.V.1, Usov V.Y.2
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Affiliations:
- Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation
- Department of X-Ray and Tomographic Diagnostic Methods, Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
- Issue: Vol 166, No 5 (2019)
- Pages: 680-685
- Section: Morphology and Pathomorphology
- URL: https://journals.rcsi.science/0007-4888/article/view/241275
- DOI: https://doi.org/10.1007/s10517-019-04417-z
- ID: 241275
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Abstract
The structure of the testicles was studied in adult rats in 120 days after a single intravenous injection of chitosan-modified (magnetic nanospheres) and lipid-modified (magnetoliposomes) nanosized magnetite particles. Perls histochemical reaction detected in the testicular interstitial connective tissue the cells which absorbed and accumulated magnetite nanoparticles. The dynamics of spermatogenesis index and the count of Perls+ cells in the rat testicles were traced throughout the experiment. The studied modified nanosized magnetite particles did not penetrate through the blood—testicle barrier in rats.
About the authors
I. V. Mil’to
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: milto_bio@mail.ru
Russian Federation, Tomsk
I. V. Sukhodolo
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation
Email: milto_bio@mail.ru
Russian Federation, Tomsk
V. V. Ivanova
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of the Russian Federation
Email: milto_bio@mail.ru
Russian Federation, Tomsk
V. Yu. Usov
Department of X-Ray and Tomographic Diagnostic Methods, Research Institute of Cardiology, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: milto_bio@mail.ru
Russian Federation, Tomsk
