Email this article Evaluation of Lipid Peroxidation—Antioxidant Defense System Depending on the Stage of Stress Reaction in Hypertensive ISIAH Rats
- Authors: Kolesnikova L.I.1, Kolesnikova L.R.1,2, Darenskaya M.A.1, Natyaganova L.V.1, Grebenkina L.A.1, Korytov L.I.2, Kolesnikov S.I.1,3
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Affiliations:
- Research Center for Family Health and Human Reproduction Problems
- Irkutsk State Medical University, Ministry of Health of the Russian Federation
- M. V. Lomonosov Moscow State University
- Issue: Vol 166, No 5 (2019)
- Pages: 610-612
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241227
- DOI: https://doi.org/10.1007/s10517-019-04402-6
- ID: 241227
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Abstract
The stages of stress reaction (anxiety and resistance) were reproduced on the model of stresssensitive hypertensive ISIAH rats. Analysis of the experimental data showed an increase in activity of the antioxidant defense system in ISIAH rats: total antioxidant activity of the blood and superoxide dismutase activity increased at the stage of anxiety and then decreased during the resistance stage.
About the authors
L. I. Kolesnikova
Research Center for Family Health and Human Reproduction Problems
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk
L. R. Kolesnikova
Research Center for Family Health and Human Reproduction Problems; Irkutsk State Medical University, Ministry of Health of the Russian Federation
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk; Irkutsk
M. A. Darenskaya
Research Center for Family Health and Human Reproduction Problems
Author for correspondence.
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk
L. V. Natyaganova
Research Center for Family Health and Human Reproduction Problems
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk
L. A. Grebenkina
Research Center for Family Health and Human Reproduction Problems
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk
L. I. Korytov
Irkutsk State Medical University, Ministry of Health of the Russian Federation
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk
S. I. Kolesnikov
Research Center for Family Health and Human Reproduction Problems; M. V. Lomonosov Moscow State University
Email: marina_darenskaya@inbox.ru
Russian Federation, Irkutsk; Moscow
