Changes in Functional Activity of Neutrophils and Monocytes Isolated from the Peripheral Blood of Women at Different Phases of the Menstrual Cycle

T. G. Smirnova; A. Yu. Savochkina; I. I. Dolgushin; K. V. Nikushkina; I. V. Samuseva

doi:10.1007/s10517-018-4318-0

Changes in Functional Activity of Neutrophils and Monocytes Isolated from the Peripheral Blood of Women at Different Phases of the Menstrual Cycle

Authors: Smirnova T.G.¹, Savochkina A.Y.¹, Dolgushin I.I.¹, Nikushkina K.V.¹, Samuseva I.V.¹
Affiliations:
1. Research Institute of Immunology, South-Ural State Medical University, Ministry of Health of the Russian Federation
Issue: Vol 166, No 2 (2018)
Pages: 222-224
Section: Immunology and Microbiology
URL: https://journals.rcsi.science/0007-4888/article/view/240918
DOI: https://doi.org/10.1007/s10517-018-4318-0
ID: 240918

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Abstract

We studied functional activity of neutrophilic granulocytes and monocytes isolated from the peripheral blood of women during the follicular and luteal phases of the menstrual cycle. It was shown that phagocytic activity of neutrophilic granulocytes increases, their intracellular oxygen-dependent bactericidal activity decreases, and the number of monocyte extracellular traps increases in women in the luteal phase of the menstrual cycle in comparison with the follicular phase.