Postgenomic Properties of Natural Micronutrients
- Authors: Sharanova N.E.1, Vasil’ev A.V.2
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Affiliations:
- V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
- Federal Research Center of Nutrition and Biotechnology
- Issue: Vol 166, No 1 (2018)
- Pages: 107-117
- Section: Supplement
- URL: https://journals.rcsi.science/0007-4888/article/view/240863
- DOI: https://doi.org/10.1007/s10517-018-4298-0
- ID: 240863
Cite item
Abstract
Modern medical approaches to the therapy of various diseases, including cancer, are based on the use of toxic drugs. The unfavorable side effects of traditional medicine could be counterbalanced by addition of natural bioactive substances to conventional therapy due to their mild action on cells combined with the multitargeted effects. To elucidate the real mechanisms of their biological activity, versatile approaches including a number of “omics” such as genomics, transcriptomics, proteomics, and metabolomics are used. This review highlights inclusion of bioactive natural compounds into the therapy of chronic diseases from the viewpoint of modern omics-based nutritional biochemistry. The recently accumulated data argue for necessity to employ nutrigenetic and nutrimetabolomic analyses to prevent or diminish the risk of chronic diseases.
About the authors
N. E. Sharanova
V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences
Author for correspondence.
Email: sharanova.natalia@gmail.com
Russian Federation, Moscow
A. V. Vasil’ev
Federal Research Center of Nutrition and Biotechnology
Email: sharanova.natalia@gmail.com
Russian Federation, Moscow