fMRI Response of Parietal Brain Areas to Sad Facial Stimuli in Mild Depression


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

fMRI markers of mild depression were revealed using standard emotional test. Patients with mild depression and healthy volunteers were asked to determine gender of subjects in photographs with different emotional expressions (neutral, surprise, disgust, confusion, anger, sadness, fear, and joy). The pattern of response to different emotions was universal in both groups and included the largest clusters in the occipital region, as well as a certain volume in the parietal lobes and posterior lateral frontal cortex. In depression group, a lack of activation in the middle cingulate gyrus (bilaterally) and in the postcentral and inferior parietal gyrus (left) in response to presentation of sad faces. For other emotion, no large clusters of intergroup contrasts significant at p<0.05 with FWE correction were revealed. The response of the middle cingulate gyrus and the left inferior parietal lobe can be considered as a potential diagnostic marker of depressive disorders and as the target for neurofeedback.

作者简介

M. Mel’nikov

Research Institute of Molecular Biology and Biophysics; Novosibirsk National Research State University

编辑信件的主要联系方式.
Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

E. Petrovskii

International Tomography Center, Siberian Division of Russian Academy of Sciences

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk

D. Bezmaternykh

Research Institute of Molecular Biology and Biophysics; Novosibirsk National Research State University

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

L. Kozlova

Research Institute of Molecular Biology and Biophysics; Novosibirsk National Research State University

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

M. Shtark

Research Institute of Molecular Biology and Biophysics; Novosibirsk National Research State University

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

A. Savelov

International Tomography Center, Siberian Division of Russian Academy of Sciences

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk

O. Shubina

Research Institute of Molecular Biology and Biophysics

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk

K. Natarova

International Institute of Psychology and Psychotherapy

Email: mikhail-melnikov@mail.ru
俄罗斯联邦, Novosibirsk

补充文件

附件文件
动作
1. JATS XML

版权所有 © Springer Science+Business Media, LLC, part of Springer Nature, 2018