Concentrations of Gaseous Transmitters during Catecholamine Damage to the Myocardium in Rats
- Authors: Ivanova A.S.1, Sitnikova O.G.2, Popova I.G.2, Nazarov S.B.1,2
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Affiliations:
- Ivanovo State Medical Academy, Ministry of Health of the Russian Federation
- V. N. Gorodkov Ivanovo Research Institute of Maternal and Child Health Care, Ministry of Health of the Russian Federation
- Issue: Vol 165, No 6 (2018)
- Pages: 725-727
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240709
- DOI: https://doi.org/10.1007/s10517-018-4251-2
- ID: 240709
Cite item
Abstract
Gaseous transmitters were assayed in rat blood during catecholamine-induced damage to the heart. Hypercatecholaminemia was modeled by single subcutaneous injection of 0.1% epinephrine hydrochloride in a dose of 2 mg/kg. The blood concentrations of NO, H2S, and CO were measured. The catecholamine-induced damage to the myocardium resulted in phasic changes in the blood levels of gaseous transmitters: CO concentration increased in 1 h, H2S increased in 24 h, and NO concentration increased in 72 h after injection.
About the authors
A. S. Ivanova
Ivanovo State Medical Academy, Ministry of Health of the Russian Federation
Author for correspondence.
Email: asivanova@mail.ru
Russian Federation, Ivanovo
O. G. Sitnikova
V. N. Gorodkov Ivanovo Research Institute of Maternal and Child Health Care, Ministry of Health of the Russian Federation
Email: asivanova@mail.ru
Russian Federation, Ivanovo
I. G. Popova
V. N. Gorodkov Ivanovo Research Institute of Maternal and Child Health Care, Ministry of Health of the Russian Federation
Email: asivanova@mail.ru
Russian Federation, Ivanovo
S. B. Nazarov
Ivanovo State Medical Academy, Ministry of Health of the Russian Federation; V. N. Gorodkov Ivanovo Research Institute of Maternal and Child Health Care, Ministry of Health of the Russian Federation
Email: asivanova@mail.ru
Russian Federation, Ivanovo; Ivanovo
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