Email this article Neurotrophic Action of Comenic Acid and Its Derivatives Potassium Comenate and Calcium Comenate
- Authors: Shurygina L.V.1, Zlishcheva E.I.1, Kravtsov A.A.1
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Affiliations:
- A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University
- Issue: Vol 165, No 4 (2018)
- Pages: 465-469
- Section: Pharmacology and Toxicology
- URL: https://journals.rcsi.science/0007-4888/article/view/240423
- DOI: https://doi.org/10.1007/s10517-018-4195-6
- ID: 240423
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Abstract
Using the model of cultured spinal ganglia, we demonstrated high neurotrophic activity of comenic acid and its derivatives potassium comenate and calcium comenate both under normal conditions and during oxidative stress. Calcium comenate in the norm as well as potassium and calcium comenates during oxidative stress demonstrate greater neurotrophic potency than comenic acid.
About the authors
L. V. Shurygina
A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University
Author for correspondence.
Email: balizfarm@mail.ru
Russian Federation, Krasnodar
E. I. Zlishcheva
A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University
Email: balizfarm@mail.ru
Russian Federation, Krasnodar
A. A. Kravtsov
A. Ya. Shurygin Department of Biologically Active Substances, Kuban State University
Email: balizfarm@mail.ru
Russian Federation, Krasnodar
