Hemodynamic Allostasis of Pregnant Women against the Background of Preeclampsia
- Authors: Zotova T.Y.1, Blagonravov M.L.1, Lapaev N.N.1, Denisova A.P.1
-
Affiliations:
- V. A. Frolov Department of General Pathology and Pathological Physiology, Medical Institute, Russian University of Peoples’ Friendship
- Issue: Vol 165, No 4 (2018)
- Pages: 440-444
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240395
- DOI: https://doi.org/10.1007/s10517-018-4189-4
- ID: 240395
Cite item
Abstract
We analyzed diurnal hemodynamic parameters (HR, systolic BP, and diastolic BP) recorded from two groups of edematous and preeclamptic pregnant women. The unidirectional character of changes in the control over the functional state of cardiovascular system was revealed except for the indices, which mark a pathological process: elevated diurnal BP in preeclampsia and diminished percentage of oscillation power in edematous patients. Uniformity of the regulatory changes in patients with and without arterial hypertension can be viewed as manifestation of allostasis developed by the cardiovascular system during pregnancy. In preeclampsia, the greater allostatic load was reflected by the changes in diurnal, daytime, and nighttime BP and in the circadian index calculated for HR, systolic BP, and diastolic BP. In edematous patients, elevation of allostatic load was indicated by the percentage of ultradian rhythms.
About the authors
T. Yu. Zotova
V. A. Frolov Department of General Pathology and Pathological Physiology, Medical Institute, Russian University of Peoples’ Friendship
Author for correspondence.
Email: zotovat@mail.ru
Russian Federation, Moscow
M. L. Blagonravov
V. A. Frolov Department of General Pathology and Pathological Physiology, Medical Institute, Russian University of Peoples’ Friendship
Email: zotovat@mail.ru
Russian Federation, Moscow
N. N. Lapaev
V. A. Frolov Department of General Pathology and Pathological Physiology, Medical Institute, Russian University of Peoples’ Friendship
Email: zotovat@mail.ru
Russian Federation, Moscow
A. P. Denisova
V. A. Frolov Department of General Pathology and Pathological Physiology, Medical Institute, Russian University of Peoples’ Friendship
Email: zotovat@mail.ru
Russian Federation, Moscow
![](/img/style/loading.gif)