Proliferative and Apoptotic Activity of Bone Marrow Monocyte Lineage Cells in the Offspring of Female Rats with Chronic Toxic Liver Injury


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Abstract

We analyzed proliferative and apoptotic activity of bone marrow monocyte lineage cells in the offspring of mothers with experimental toxic injury to the liver. Rat pups were examined at different times of ontogeny. Inhibition of proliferative activity and increase in apoptotic activity in bone marrow monocyte cells of experimental rat pups in comparison with intact ones were found.

About the authors

G. V. Bryukhin

South Ural State Medical University, Ministry of Health of the Russian Federation

Email: t-komm@mail.ru
Russian Federation, Chelyabinsk

T. M. Komarova

Chelyabinsk State University

Author for correspondence.
Email: t-komm@mail.ru
Russian Federation, Chelyabinsk


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