Email this article Effect of Vitrification on Functional Morphology and Viability of the Ovarian Tissue
- Authors: Yuzhakov V.V.1, Malinova I.V.1, Kiseleva M.V.1, Fomina N.K.1, Bandurko L.N.1, Komarova E.V.1, Sevan’kaeva L.E.1, Ingel’ I.E.1, Yakovleva N.D.1, Kaprin A.D.1
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Affiliations:
- A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
- Issue: Vol 164, No 4 (2018)
- Pages: 502-507
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239715
- DOI: https://doi.org/10.1007/s10517-018-4021-1
- ID: 239715
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Abstract
The results of a complex morphofunctional study with markers of proliferation (PCNA and Ki-67), angiogenesis (CD31 and CD34), and structural integrity of mesenchymal cells (vimentin) suggest that the pool of primordial follicles was well preserved in vitrified ovarian tissue and that viability of its cellular components can be rapidly restored during incubation at 37°C within 4 h after thawing.
About the authors
V. V. Yuzhakov
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
I. V. Malinova
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: imal2000@mail.ru
Russian Federation, Obninsk
M. V. Kiseleva
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
N. K. Fomina
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
L. N. Bandurko
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
E. V. Komarova
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
L. E. Sevan’kaeva
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
I. E. Ingel’
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
N. D. Yakovleva
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
A. D. Kaprin
A. Tsyb Medical Radiological Research Center — Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation
Email: imal2000@mail.ru
Russian Federation, Obninsk
