Email this article A Marker of Cerebral Ischemia in Solid State Structures of Blood Serum
- Authors: Shatokhina S.N.1, Aleksandrin V.V.1, Shatokhina I.S.2, Kubatiev A.A.1, Shabalin V.N.1
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Affiliations:
- Research Institute of General Pathology and Pathophysiology
- M. F. Vladimirsky Moscow Regional Research and Clinical Institute, the Ministry of Health of the Russian Federation
- Issue: Vol 164, No 3 (2018)
- Pages: 366-370
- Section: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/239604
- DOI: https://doi.org/10.1007/s10517-018-3991-3
- ID: 239604
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Abstract
Reversible cerebral ischemia of medium severity was reproduced in male Wistar rats by bilateral occlusion of the common carotid arteries. Solid-phase structures (anisomorphons) were obtained by marginal dehydration of the serum. Small focal isotropic defects in the serum anisomorphon texture were found in 100% cases during occlusion of the carotid arteries. Similar signs were detected in all patients with chronic cerebral ischemia, which proved specificity of this morphological marker of the disease.
About the authors
S. N. Shatokhina
Research Institute of General Pathology and Pathophysiology
Author for correspondence.
Email: sv_n@list.ru
Russian Federation, Moscow
V. V. Aleksandrin
Research Institute of General Pathology and Pathophysiology
Email: sv_n@list.ru
Russian Federation, Moscow
I. S. Shatokhina
M. F. Vladimirsky Moscow Regional Research and Clinical Institute, the Ministry of Health of the Russian Federation
Email: sv_n@list.ru
Russian Federation, Moscow
A. A. Kubatiev
Research Institute of General Pathology and Pathophysiology
Email: sv_n@list.ru
Russian Federation, Moscow
V. N. Shabalin
Research Institute of General Pathology and Pathophysiology
Email: sv_n@list.ru
Russian Federation, Moscow
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