Email this article Effect of Skin Application of Dorogov’s Antiseptic-Stimulant on Behavioral Reactions in Rats
- Authors: Piavchenko G.A.1,2, Dutta P.2, Novikova N.S.3, Pugach V.A.3, Korneva E.A.3, Nozdrin V.I.1,2
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Affiliations:
- Center for Preclinical Research, Retinoids Company
- Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University
- Department of General Pathology and Pathophysiology, Institute of Experimental Medicine
- Issue: Vol 163, No 5 (2017)
- Pages: 677-680
- Section: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/239188
- DOI: https://doi.org/10.1007/s10517-017-3877-9
- ID: 239188
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Abstract
Local application of the Dorogov’s antiseptic-stimulant onto the skin of 2-month-old male Sprague-Dawley rats in a low dose (0.5 g/kg/day) for 1 week increased motor and ultrasonic activity of experimental animals and the content of activated c-Fos+ neurons on the cingular, motor, insular, and pyriform cortex and in the striatum.
About the authors
G. A. Piavchenko
Center for Preclinical Research, Retinoids Company; Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University
Author for correspondence.
Email: gennadii.piavchenko@yandex.ru
Russian Federation, Moscow; Orel
P. Dutta
Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University
Email: gennadii.piavchenko@yandex.ru
Russian Federation, Orel
N. S. Novikova
Department of General Pathology and Pathophysiology, Institute of Experimental Medicine
Email: gennadii.piavchenko@yandex.ru
Russian Federation, St. Petersburg
V. A. Pugach
Department of General Pathology and Pathophysiology, Institute of Experimental Medicine
Email: gennadii.piavchenko@yandex.ru
Russian Federation, St. Petersburg
E. A. Korneva
Department of General Pathology and Pathophysiology, Institute of Experimental Medicine
Email: gennadii.piavchenko@yandex.ru
Russian Federation, St. Petersburg
V. I. Nozdrin
Center for Preclinical Research, Retinoids Company; Department of Histology, Cytology, and Embryology, Institute of Medicine, I. S. Turgenev Orel State University
Email: gennadii.piavchenko@yandex.ru
Russian Federation, Moscow; Orel
