Matrixins in the Salivary Fluid of Patients with Tumors of the Maxillofacial Region during Orthopedic Rehabilitation with Different Prosthetic Structures
- Authors: Kochurova E.V.1, Nikolenko V.N.1
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Affiliations:
- I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 163, No 5 (2017)
- Pages: 663-666
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239175
- DOI: https://doi.org/10.1007/s10517-017-3874-z
- ID: 239175
Cite item
Abstract
Dental and immunological features of the influence of various prosthetic structures of orthopedic prostheses on tissues and organs of the maxillofacial region were evaluated by the parameters of expression of oral fluid biomarkers. Healthy people without tumor and somatic diseases and patients with neoplasms of maxillofacial area in need of dental rehabilitation were examined before and in 2 weeks and 3 months after treatment. Certain regularities in the reaction of biomarkers to orthopedic prostheses were observed: a decrease in activity of MMP-2 and MMP-8 and their inhibitors or an increase in MMP-9; an increase in activity of biomarkers at early terms and a decrease in delayed terms after prosthetics.
About the authors
E. V. Kochurova
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Author for correspondence.
Email: evkochurova@mail.ru
Russian Federation, Moscow
V. N. Nikolenko
I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: evkochurova@mail.ru
Russian Federation, Moscow