Plasma Level of hsa-miR-619-5p microRNA Is Associated with Prostatic Cancer Dissemination beyond the Capsule


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Abstract

Profiles of circulating microRNA in the plasma of patients with prostate cancer with pathomorphological stages pT2, pT3, and pT4 are analyzed. The level of circulating microRNA hsa-miR-619-5p is elevated in patients with extracapsular spreading of the tumor, increasing significantly from stage pT2 to stage pT4.

About the authors

M. Yu. Shkurnikov

BioClinicum Research Centre; P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia

Author for correspondence.
Email: mshkurnikov@gmail.com
Russian Federation, Moscow; Moscow

Yu. A. Makarova

BioClinicum Research Centre

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

E. N. Knyazev

BioClinicum Research Centre; P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia

Email: mshkurnikov@gmail.com
Russian Federation, Moscow; Moscow

K. A. Fomicheva

P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

A. V. Galatenko

BioClinicum Research Centre

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

K. M. Nyushko

P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

V. V. Galatenko

BioClinicum Research Centre

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

V. I. Vechorko

Federal Research Institute of Health Organization and Informatics, Ministry of Health of the Russian Federation

Email: mshkurnikov@gmail.com
Russian Federation, Moscow

B. Ya. Alekseev

P. A. Herzen Moscow Oncology Research Institute, Affiliated Branch of National Medical Research Radiology Center, Ministry of Health of Russia

Email: mshkurnikov@gmail.com
Russian Federation, Moscow


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