Email this article Magnetic Resonance Imaging of Tumors with the Use of Iron Oxide Magnetic Nanoparticles as a Contrast Agent
- Authors: Semkina A.S.1, Abakumov M.A.1,2, Grinenko N.F.3, Lipengolts A.A.4,5, Nukolova N.V.3, Chekhonin V.P.1,3
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Affiliations:
- N. I. Pirogov Russian National Research Medical University
- MISiS National Research Technological University
- V. P. Serbsky Federal Medical Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation
- N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation
- MIFI National Research Nuclear University
- Issue: Vol 162, No 6 (2017)
- Pages: 808-811
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238590
- DOI: https://doi.org/10.1007/s10517-017-3718-x
- ID: 238590
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Abstract
We studied the possibility of using BSA-coated magnetic iron oxide nanoparticles for magnetic resonance imaging diagnosis of C6 glioblastoma, 4T1 mammary adenocarcinoma, and RS-1 hepatic mucous carcinoma. In all three cases, magnetic nanoparticles accumulated in the tumor and its large vessels. Magnetic resonance imaging with contrast agent allows visualization of the tumor tissue and its vascularization.
About the authors
A. S. Semkina
N. I. Pirogov Russian National Research Medical University
Author for correspondence.
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow
M. A. Abakumov
N. I. Pirogov Russian National Research Medical University; MISiS National Research Technological University
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow; Moscow
N. F. Grinenko
V. P. Serbsky Federal Medical Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow
A. A. Lipengolts
N. N. Blokhin Russian Cancer Research Center, Ministry of Health of the Russian Federation; MIFI National Research Nuclear University
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow; Moscow
N. V. Nukolova
V. P. Serbsky Federal Medical Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow
V. P. Chekhonin
N. I. Pirogov Russian National Research Medical University; V. P. Serbsky Federal Medical Center of Psychiatry and Narcology, Ministry of Health of the Russian Federation
Email: alevtina.semkina@gmail.com
Russian Federation, Moscow; Moscow
