Email this article Systemic Amyloidosis Model on Young Mice
- Authors: Kozlov V.A.1, Sapozhnikov S.P.1, Karyshev P.B.2, Sheptukhina A.I.1, Nikolaeva O.V.1
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Affiliations:
- Department of Medical Biology with a Course of Microbiology and Virology
- Department of Common, Clinical Pathology and Forensic Medicine, I. N. Ulyanov Chuvash State University
- Issue: Vol 162, No 4 (2017)
- Pages: 520-523
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238338
- DOI: https://doi.org/10.1007/s10517-017-3652-y
- ID: 238338
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Abstract
Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.
About the authors
V. A. Kozlov
Department of Medical Biology with a Course of Microbiology and Virology
Author for correspondence.
Email: pooh12@yandex.ru
Russian Federation, Cheboksary
S. P. Sapozhnikov
Department of Medical Biology with a Course of Microbiology and Virology
Email: pooh12@yandex.ru
Russian Federation, Cheboksary
P. B. Karyshev
Department of Common, Clinical Pathology and Forensic Medicine, I. N. Ulyanov Chuvash State University
Email: pooh12@yandex.ru
Russian Federation, Cheboksary
A. I. Sheptukhina
Department of Medical Biology with a Course of Microbiology and Virology
Email: pooh12@yandex.ru
Russian Federation, Cheboksary
O. V. Nikolaeva
Department of Medical Biology with a Course of Microbiology and Virology
Email: pooh12@yandex.ru
Russian Federation, Cheboksary
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