Email this article Analgesic Effect of Xenon in Rat Model of Inflammatory Pain
- Authors: Kukushkin M.L.1,2, Igon’kina S.I.1, Potapov S.V.1, Potapov A.V.1
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Affiliations:
- Research Institute of General Pathology and Pathological Physiology
- I. M. Sechenov First Moscow State Medical University
- Issue: Vol 162, No 4 (2017)
- Pages: 451-453
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238290
- DOI: https://doi.org/10.1007/s10517-017-3637-x
- ID: 238290
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Abstract
The analgesic effects of inert gas xenon were examined on rats. The formalin model of inflammatory pain, tail-flick test, and hot-plate test revealed the antinociceptive effects of subanesthetizing doses of inhalation anesthetic xenon. Inhalation of 50/50 xenon/oxygen mixture moderated the nociceptive responses during acute and tonic phases of inflammatory pain.
About the authors
M. L. Kukushkin
Research Institute of General Pathology and Pathological Physiology; I. M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: mkuk57@gmail.com
Russian Federation, Moscow; Moscow
S. I. Igon’kina
Research Institute of General Pathology and Pathological Physiology
Email: mkuk57@gmail.com
Russian Federation, Moscow
S. V. Potapov
Research Institute of General Pathology and Pathological Physiology
Email: mkuk57@gmail.com
Russian Federation, Moscow
A. V. Potapov
Research Institute of General Pathology and Pathological Physiology
Email: mkuk57@gmail.com
Russian Federation, Moscow
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