Effect of Natural and 24-h Illumination on Mesenchymal Stem Cells

A. P. Lykov; N. A. Bondarenko; M. A. Surovtseva; I. I. Kim; O. V. Poveshchenko; I. Yu. Ishchenko; A. V. Kabakov; O. V. Kazakov; A. F. Poveshchenko; E. L. Zav’yalov; S. V. Michurina; V. I. Konenkov

doi:10.1007/s10517-016-3562-4

Effect of Natural and 24-h Illumination on Mesenchymal Stem Cells

Authors: Lykov A.P.¹, Bondarenko N.A.¹, Surovtseva M.A.¹, Kim I.I.¹, Poveshchenko O.V.¹, Ishchenko I.Y.¹, Kabakov A.V.¹, Kazakov O.V.¹, Poveshchenko A.F.¹, Zav’yalov E.L.², Michurina S.V.¹, Konenkov V.I.¹
Affiliations:
1. Research Institute of Clinical and Experimental Lymphology
2. Federal Research Institute Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Issue: Vol 162, No 1 (2016)
Pages: 134-137
Section: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
URL: https://journals.rcsi.science/0007-4888/article/view/237977
DOI: https://doi.org/10.1007/s10517-016-3562-4
ID: 237977

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Abstract

We studied the effect 24-h illumination on quantitative and qualitative parameters of the bone marrow cells in Wistar rats. It was shown that desynchronosis reduced the release of nucleated cells from the femoral bone, while melatonin weakened this effect. The number of bone marrow mesenchymal stromal cells was resistant to circadian rhythm disturbances, while proliferation depended on glucose concentration in the medium.