Email this article Inhibition of Tobacco Ringspot Virus by the Culture Fluid of L-Lysine-α-Oxidase Producing Strain
- Authors: Shneider Y.A.1, Smirnova I.P.1, Karimova E.V.1
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Affiliations:
- Medical Faculty, Medical Institute, Peoples’ Friendship University of Russia
- Issue: Vol 162, No 1 (2016)
- Pages: 79-81
- Section: Virology
- URL: https://journals.rcsi.science/0007-4888/article/view/237926
- DOI: https://doi.org/10.1007/s10517-016-3550-8
- ID: 237926
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Abstract
A producing strain of an anti-tumor and antiviral enzyme L-lysine-α-oxidase from Trichoderma was cultured using a technological device of G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences (Pushchino). L-lysine-α-oxidase activity in the obtained metabolite concentrate was 5.4 U/ml. We studied the effects of the concentrate of active L-lysine-α-oxidase producer on the highly infectious Tobacco ringspot virus and revealed anti-viral activity of it when enzyme concentration was at least 1.0 U/ml.
About the authors
Yu. A. Shneider
Medical Faculty, Medical Institute, Peoples’ Friendship University of Russia
Email: smir-ip@yandex.ru
Russian Federation, Moscow
I. P. Smirnova
Medical Faculty, Medical Institute, Peoples’ Friendship University of Russia
Author for correspondence.
Email: smir-ip@yandex.ru
Russian Federation, Moscow
E. V. Karimova
Medical Faculty, Medical Institute, Peoples’ Friendship University of Russia
Email: smir-ip@yandex.ru
Russian Federation, Moscow
