Effectiveness of Lifestyle Modification in Corrections of States Associated with Metabolic Syndrome


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Abstract

In a 3-month study, 30 obese patients were assigned to lifestyle modification therapy, which is the major component of all modern strategies correcting the metabolic syndrome. The 3-month course of non-pharmacological therapy significantly diminished the major index evaluating the state of these patients, i.e., the risk of cardiovascular disasters. This therapy positively affected all the states associated with metabolic syndrome: arterial BP attained the targets in 53% patients together with normalization of their nocturnal arterial BP dipping status; the lipid panel and carbohydrate metabolic indices normalized in 46 and 44% patients, respectively; hepatic steatosis moderated in 56% patients; and the disturbances in hemostasis were annihilated in 67% patients.

About the authors

S. I. Kseneva

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine

Author for correspondence.
Email: viksbest@mail.ru
Russian Federation, Tomsk

E. V. Borodulina

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine

Email: viksbest@mail.ru
Russian Federation, Tomsk

O. Yu. Trifonova

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine

Email: viksbest@mail.ru
Russian Federation, Tomsk

V. V. Udut

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine; National Research Tomsk State University

Email: viksbest@mail.ru
Russian Federation, Tomsk; Tomsk


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