Antiviral Activity of Ergoferon against Group A Rotavirus


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Abstract

Antiviral activity of Ergoferon was studied in vitro on an experimental model of rotavirus infection in MA-104 cell line. In infected cells treated with Ergoferon, rotavirus titer was shown to decrease by 83 and 90% in comparison with cells treated with solvent used for Ergoferon preparation (p<0.05) and distilled water (p<0.05), respectively. These findings demonstrate high anti-rotavirus activity of Ergoferon.

About the authors

A. G. Emelianova

Laboratory of Physiologically Active Substances, Department of Molecular and Cellular Pathology and Pathophysiology, Research Institute of General Pathology and Pathophysiology

Author for correspondence.
Email: agemelianova@gmail.com
Russian Federation, Moscow

I. P. Shilovskii

State Research Center Institute of Immunology, Federal Medical-Biological Agency

Email: agemelianova@gmail.com
Russian Federation, Moscow

M. S. Sundukova

State Research Center Institute of Immunology, Federal Medical-Biological Agency

Email: agemelianova@gmail.com
Russian Federation, Moscow

M. R. Khaitov

State Research Center Institute of Immunology, Federal Medical-Biological Agency

Email: agemelianova@gmail.com
Russian Federation, Moscow

O. I. Epshtein

Laboratory of Physiologically Active Substances, Department of Molecular and Cellular Pathology and Pathophysiology, Research Institute of General Pathology and Pathophysiology

Email: agemelianova@gmail.com
Russian Federation, Moscow


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