Characteristics of Factors of Protozoa Blastocystis hominis Persistence
- Authors: Potaturkina-Nesterova N.I.1, Il’ina N.A.1,2, Bugero N.V.1,2, Nesterov A.S.1
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Affiliations:
- Department of General and Clinical Pharmacology with Microbiology Course, Ulyanovsk State University
- I. N. Ulyanov Ulyanovsk State Pedagogical University
- Issue: Vol 161, No 6 (2016)
- Pages: 804-805
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237798
- DOI: https://doi.org/10.1007/s10517-016-3515-y
- ID: 237798
Cite item
Abstract
Persistence activity manifested in the expression of anti-lysozyme, anti-lactoferrin, and antihistone factors promoting inactivation of natural anti-infection resistance factors in the body was revealed in Blastocystis hominis protozoa. Activities of these factors were ranged. The frequency of these factors in clinical isolates of blastocyst decreased in the following order: anti-lactoferrin activity (84.5±3.7%)→anti-lysozyme activity (64.8±5.7%)→anti-histone activity (48.1±2.3%). In healthy humans, the corresponding parameters were 7.3±1.3, 5.3±0.9, and 3.3±0.4%, respectively (p<0.05). It was shown that the studied activities in highly virulent blastocysts were higher than in groups of medium-, low-, and avirulent protozoa.
About the authors
N. I. Potaturkina-Nesterova
Department of General and Clinical Pharmacology with Microbiology Course, Ulyanovsk State University
Author for correspondence.
Email: sgmikm@gmail.com
Russian Federation, Ulyanovsk
N. A. Il’ina
Department of General and Clinical Pharmacology with Microbiology Course, Ulyanovsk State University; I. N. Ulyanov Ulyanovsk State Pedagogical University
Email: sgmikm@gmail.com
Russian Federation, Ulyanovsk; Ulyanovsk
N. V. Bugero
Department of General and Clinical Pharmacology with Microbiology Course, Ulyanovsk State University; I. N. Ulyanov Ulyanovsk State Pedagogical University
Email: sgmikm@gmail.com
Russian Federation, Ulyanovsk; Ulyanovsk
A. S. Nesterov
Department of General and Clinical Pharmacology with Microbiology Course, Ulyanovsk State University
Email: sgmikm@gmail.com
Russian Federation, Ulyanovsk