Email this article Effect of Coenzyme Q10 on Proteomic Profile of Rat Brain Amygdala during Acute Metabolic Stress
- Authors: Kirbaeva N.V.1, Sharanova N.E.1, Zhminchenko V.M.1, Toropygin I.Y.2, Koplik E.V.3, Pertsov S.S.3, Vasil’ev A.V.1
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Affiliations:
- Research Institute of Nutrition, Russian Academy of Medical Sciences
- Center of Common Use “Human Proteome”, V. I. Orekhovich Research Institute of Biomedical Chemistry
- P. K. Anokhin Research Institute of Normal Physiology
- Issue: Vol 161, No 4 (2016)
- Pages: 460-464
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237515
- DOI: https://doi.org/10.1007/s10517-016-3438-7
- ID: 237515
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Abstract
Differences in the proteomic profiles of the brain amygdala in rats with different prognostic resistance to stress were found on the model of metabolic stress. Differential expression of tropomodulin-2, GTP-binding protein SAR1, peroxiredoxin-2, calcineurin B homologous protein 1, Ras-related protein Rab-14, glutathione S-transferase omega-1, Tcrb protein, and NADH dehydrogenase [ubiquinone] iron-sulfur protein 8 (mitochondrial) was shown to depend on the behavioral pattern of animals and stage of the study. Specific features were observed in the involvement of the amygdala in the stress response of specimens with various behavioral characteristics.
About the authors
N. V. Kirbaeva
Research Institute of Nutrition, Russian Academy of Medical Sciences
Author for correspondence.
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
N. E. Sharanova
Research Institute of Nutrition, Russian Academy of Medical Sciences
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
V. M. Zhminchenko
Research Institute of Nutrition, Russian Academy of Medical Sciences
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
I. Yu. Toropygin
Center of Common Use “Human Proteome”, V. I. Orekhovich Research Institute of Biomedical Chemistry
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
E. V. Koplik
P. K. Anokhin Research Institute of Normal Physiology
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
S. S. Pertsov
P. K. Anokhin Research Institute of Normal Physiology
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
A. V. Vasil’ev
Research Institute of Nutrition, Russian Academy of Medical Sciences
Email: n.kirbaeva@gmail.com
Russian Federation, Moscow
