Cell Composition of Central and Peripheral Lymphoid Organs of Wistar Rats Treated with a Biomedical Cell Product

V. I. Konenknov; Yu. I. Borodin; T. I. Dergacheva; A. V. Shurlygina; E. V. Mel’nikova; M. V. Tenditnik; E. V. Starkova; A. P. Lykov; O. V. Poveshchenko; N. A. Bondarenko; I. I. Kim

doi:10.1007/s10517-016-3366-6

Cell Composition of Central and Peripheral Lymphoid Organs of Wistar Rats Treated with a Biomedical Cell Product

Authors: Konenknov V.I.¹, Borodin Y.I.¹, Dergacheva T.I.¹, Shurlygina A.V.², Mel’nikova E.V.², Tenditnik M.V.², Starkova E.V.¹, Lykov A.P.¹, Poveshchenko O.V.¹, Bondarenko N.A.¹, Kim I.I.¹
Affiliations:
1. Research Institute of Clinical and Experimental Lymphology
2. Research Institute of Physiology and Fundamental Medicine
Issue: Vol 161, No 1 (2016)
Pages: 150-154
Section: Article
URL: https://journals.rcsi.science/0007-4888/article/view/237210
DOI: https://doi.org/10.1007/s10517-016-3366-6
ID: 237210

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Abstract

We studied the effect of a biomedical cell product (bone marrow multipotent mesenchymal stromal cells and products secreted by these cells in conditioned medium) on subpopulation composition of lymphoid cells of central and peripheral lymphoid organs of Wistar rats under normal conditions. Changes in the subpopulation composition of lymphoid organs depended on the route of administration of biomedical cell product.