Analysis of Antiviral Properties of Hexoral In Vitro against Some Viruses that Cause Acute Respiratory Infections and Herpes
- Authors: Deryabin P.G.1, Galegov G.A.1, Andronova V.A.1, Botikov A.G.1
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Affiliations:
- D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- Issue: Vol 160, No 3 (2016)
- Pages: 353-356
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236705
- DOI: https://doi.org/10.1007/s10517-016-3169-9
- ID: 236705
Cite item
Abstract
Antiviral properties of Hexoral (0.1% solution and 0.2% aerosol for local application) and its constituent hexetidine against viruses causing human respiratory tract infections and herpes virus were studied in vitro. It was found that non-cytotoxic concentrations of hexetidine (alone and as a component of Hexoral) attenuated infectious properties of highly virulent influenza virus A/H5N1, pandemic influenza virus A/H1N1pdm, respiratory syncytial virus, and herpes simplex virus type 1 after a short-term exposure (30 sec) by 100 or more times. It was found that hexidine mostly contributes to the virucidal effect of Hexoral.
About the authors
P. G. Deryabin
D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Author for correspondence.
Email: pg_deryabin@mail.ru
Russian Federation, Moscow
G. A. Galegov
D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: pg_deryabin@mail.ru
Russian Federation, Moscow
V. A. Andronova
D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: pg_deryabin@mail.ru
Russian Federation, Moscow
A. G. Botikov
D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: pg_deryabin@mail.ru
Russian Federation, Moscow
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