Email this article Influence of High Blood Pressure on Microcirculation in Cerebral Cortex of Young Rats
- Authors: Sokolova I.B.1, Sergeev I.V.1, Dvoretskii D.P.1
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Affiliations:
- Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
- Issue: Vol 160, No 3 (2016)
- Pages: 298-299
- Section: General Pathology and Pathophysiology
- URL: https://journals.rcsi.science/0007-4888/article/view/236691
- DOI: https://doi.org/10.1007/s10517-016-3155-2
- ID: 236691
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Abstract
We studied the density and structure of the microvascular network of the pia mater, the blood flow rate and oxygen saturation in the sensorimotor cortex of young spontaneously hypertensive rats (SHR). The density of the microvascular network in hypertensive animals was by ~1.4 times lower than in normotensive Wistar-Kyoto rats (control) and arteriolar bed density was lower by ~1.9 times. The blood flow rate in tissue and oxygen saturation in the sensorimotor cortex in SHR rats were significantly lower than in control animals.
About the authors
I. B. Sokolova
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Author for correspondence.
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
I. V. Sergeev
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
D. P. Dvoretskii
Laboratory of Physiology of Cardiovascular and Lymphatic Systems, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences
Email: sib@kolt.infran.ru
Russian Federation, St. Petersburg
