Electrical Stimulation of Human Connective Tissue Cells on Layers of Composite Structures with a Nanocarbon Framework


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A technique for electrical stimulation of growth of connective tissue cells on composite structures with a nanocarbon framework was developed. Cells were stimulated with pulsed electric signal (amplitude, 200 mV; pulse duration, 2.5 ms) for 5 h. A study of the effect of the electrical stimulation on the viability of cells showed an increase in the proliferative activity and in the density of cells adhering to the surface of composite structure layers. The aspect ratio for the cell structure subjected to the electrical stimulation was 1.4 times greater than for nonstimulated cells. The developed technique can be used in tissue engineering, an important branch of regenerative medicine.

作者简介

M. Mezentseva

Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya

Email: gerasimenko@bms.zone
俄罗斯联邦, Moscow

L. Russu

Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya

Email: gerasimenko@bms.zone
俄罗斯联邦, Moscow

P. Privalova

National Research University of Electronic Technology (MIET)

Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow

A. Gerasimenko

National Research University of Electronic Technology (MIET); I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow; Moscow

N. Zhurbina

National Research University of Electronic Technology (MIET)

Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow

V. Petukhov

National Research University of Electronic Technology (MIET)

Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow

E. Pyankov

National Research University of Electronic Technology (MIET)

Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow

L. Ichkitidze

National Research University of Electronic Technology (MIET); I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: gerasimenko@bms.zone
俄罗斯联邦, Zelenograd, Moscow; Moscow

I. Suetina

Ivanovsky Institute of Virology, National Research Center for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya

Email: gerasimenko@bms.zone
俄罗斯联邦, Moscow

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